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Wednesday, October 06, 2010

Congratulations to Prof. Ei-ichi Negishi for 2010 Nobel Prize in Chemistry!

諾貝爾化學獎由日本和美國三位科學家分享,包括北海道大學名譽教授鈴木章、美國普渡大學的日籍教授根岸英一、以及美國學者赫克。 瑞皇皇家科學院表示,是要表揚三人在有機合成領域研究的貢獻。 報道說,有關研究有助醫學、電子及農業發展。

Purdue Newsroom - Purdue professor wins Nobel Prize in chemistry

Purdue professor wins Nobel Prize in chemistryOctober 6, 2010WEST LAFAYETTE, Ind. - A Purdue University chemist on Wednesday (Oct. 6) was awarded the Nobel Prize in chemistry for creating a method to build complex organic molecules necessary for numerous purposes, from pharmaceutical manufacturing to electronics.

Ei-ichi Negishi (pronounced "H. Na-gE-shE"), the Herbert C. Brown Distinguished Professor of Chemistry, was a co-recipient of the prize with scientists Richard Heck of the University of Delaware in Newark and Akira Suzuki of Hokkaido University in Sapporo, Japan. They will share the $1.5 million award.


Purdue President France A. Córdova said the university was proud that Negishi and his work were recognized by the Nobel Prize committee."Ei-ichi Negishi's work in organic molecules is groundbreaking and inspiring, especially in its application for improving medicines and impacting lives," Córdova said. "We are very proud that he has been bestowed with this highest honor. We congratulate professor Negishi and celebrate this great accomplishment."


Negishi developed metal-based reactions, called palladium-catalyzed cross-coupling, that allow for easy and efficient synthesis of complex organic compounds. Examples of applications include drug manufacturing, fluorescent marking that has been essential for DNA sequencing and creating materials for thin LED displays. He discovered catalytic reactions using a number of transition metals that allow various organic compounds to be synthesized widely, efficiently and selectively for use in fields ranging from medicine to materials development. His work has resulted in dramatically reducing the cost of using such metals, like palladium, in the synthesis.


"Catalysts are not lost as they spur a chemical reaction, they are recycled and can be used over and over again," he said. "These transition metals are very expensive, but when they can be used millions to billions of times, it dramatically reduces the cost and makes the mass manufacturing of special, complex materials practical."Negishi likened the innovation to playing with a LEGO game, altering the building blocks of molecules and using transition metals as catalysts to promote the reactions needed for the synthesis."We found catalysts and created reactions that allow complex organic compounds to, in effect, snap together with other compounds to more economically and efficiently build desired materials," he said. "LEGOs can be combined to make things of any shape, size and color, and our reactions make this a possibility for organic compounds."

(read more)

Writers:
Elizabeth K. Gardner, 765-494-2081, ekgardner@purdue.edu
Emil Venere, 765-494-4709, venere@purdue.edu
Related information:
Purdue's Nobel Prize morning news conference ; afternoon (English) news conference
Nobel Prize afternoon news (Japanese) conference

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